ABSTRACT
Pandemics are large-scale outbreaks of contagious disease that can significantly raise ill health and promote death. Pandemics can spread through, wide range of geographical areas across the globe and capable of disrupting social and economic status of the countries affected. With the scientific testimony available it is evidenced that the rate of occurrence of pandemics has been drastically increased over the last two decades and presently witnessing the impact of COVID-19 disease globally. Anthropogenic activities such as urbanization conditions, increased global travel, abnormal land usage, exploitation of natural environment, are some of the significant causative factors that promote the rate of occurrence of pandemics. Rapid spread of SARS-CoV-2 virus highlighted the importance such as, be ready for any imminent event, need of detecting new bacterial and viral pathogens at initial stages of contagion and focus on the risk elements that promote the occurrence and spread of the outbreaks to humankind. It is evidenced from the literature that, there is a great demand to institute the methodological process using smart approaches such as Insilco based studies to investigate the emergence of future pandemics. Globally there is a great demand for the robust and efficient procedures to develop novel biomolecule in quick period. With this significance, the present paper aimed to survey the occurrence of global pandemics and the applications of Insilco methods in identifying newer routes to develop novel biomolecules in challenge the existing, newly emerging, resurging, deliberately emerging global outbreaks. © 2022 Published by ISRES Publishing: www.isres.org.